Helicobacter pylori and Epstein–Barr Virus Infection in Gastric Diseases: Correlation with IL-10 and IL1RN Polymorphism

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Presence of cagA Gene in Patients with Gastric Cancer and Gastritis with Helicobacter pylori Infection

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[Helicobacter pylori infection in peptic ulcer and gastric cancer diseases].

胃 お よ び 十 二 指 腸 潰 瘍 は消 化 性 潰 瘍 と呼 ば れ て お り,日 本 人 で は特 に 胃潰 瘍 の頻 度 が 高 い.そ の 原 因 と して 「no acid no ulcer」 と言 わ れ る よ う に,胃 酸 が そ の主 役 を つ とめ,ス トレ ス,非 ス テ ロ イ ド系 消 炎 鎮 痛 剤 な どが 発 生 の脇 役 を つ とめ る と理 解 され て きた.現 在 で も,H2-プ ロ ッカ ー,プ ロ トンポ ン プ ・有 ン ヒ ビ ター(PPDに 代 表 され る, 胃酸 分 泌 抑 制 剤 が 潰 瘍 治 療 の 中 心 で あ り,粘 膜 保 護 剤 で 潰 瘍 治 癒 を促 進 させ る と い う治 療 法 に は 変 わ りが な い.ま た,H2-プ ロ ッ カ ー の登 場 は 潰 瘍 外 科 治 療 を激 変 ...

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Introduction: In addition to Helicobacter pylori, non-Helicobacter pylori helicobacters (NHPHs) have been diagnosed in the humans stomach that caused gastrointestinal diseases. This study aimed to evaluate the coinfection of H. pylori with NHPHs species in patients with gastric disorders in Iran.   Materials & Methods: This cross-sectional study was performed on 421 gastric biopsies form dysp...

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Background: Attempts for early detection of gastric cancer have recently focused on host's genetic susceptibility factors and gene-environment interactions. We have, herein, studied the association of MTHFR C677T single nucleotide polymorphism (SNP) and its interaction with Helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an Iranian population. Methods:...

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Background: Polymorphisms in the immune related genes are important in the clinical outcome of Helicobacter pylori infection. Myeloperoxidase -463 G/A polymorphism has been shown to reduce enzyme expression and activity. Objective: the aim of the present study is to investigate the association of myeloperoxidase G-463A polymor-phism with clinical outcome of Helicobacter pylori infection. Method...

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ژورنال

عنوان ژورنال: Journal of Oncology

سال: 2019

ISSN: 1687-8450,1687-8469

DOI: 10.1155/2019/1785132